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DIR Researcher Profile: Dr. Pamela Tamez

Dr. Pamela Tamez

Pamela Tamez, PhD
Training Director
Division of Intramural Research

301-451-5895
tamezpa@mail.nih.gov

Research

Topic: Genomics, gene expression, omics technologies, career development and training

Experience

  • Joined the NINR Office of the Training Director in the Division of Intramural Research (DIR) in 2015
    • Spearheads training activities, including the Summer Genetics Institute, the Graduate Partnerships Program, and the Methodologies Boot Camp
    • Actively involved in recruiting, training, and mentoring summer interns, intramural fellows, and research staff at all levels in the DIR
  • Initiated and implemented career development programs in the Office of Training and Diversity at the National Institute of Allergy and Infectious Diseases (NIAID)
    • Promoted career development of intramural trainees
    • Led a series of grant writing courses and organized seminars to highlight the many career paths available to scientists

Accomplishments

  • Curated and annotated genes from multiple species for RefSeq at The National Library of Medicine
  • Developed a new malaria infection model using hematopoietic stem cells
  • Spearheaded project to characterize novel drug leads by building state-of-the-art gene expression platform

Education

  • PhD, Drug Discovery, University of Illinois at Chicago

Selected Publications

  1. Empowering Clinician-Scientists in the Information Age of Omics and Data Science.
    Tamez, PA, Engler, MB. In Actionable Intelligence in Healthcare. Edited by Jay Liebowitz and Amanda Dawson. 2017; 1-18. Boca Raton: Taylor & Francis.
  2. RefSeq: an update on mammalian reference sequences.
    Pruitt KD, Brown GR, Hiatt SM, Thibaud-Nissen F, Astashyn A, Ermolaeva O, Farrell CM, Hart J, Landrum MJ, McGarvey KM, Murphy MR, O'Leary NA, Pujar S, Rajput B, Rangwala SH, Riddick LD, Shkeda A, Sun H, Tamez P, Tully RE, Wallin C, Webb D, Weber J, Wu W, DiCuccio M, Kitts P, Maglott DR, Murphy TD, Ostell JM.
    Nucleic Acids Res. 2014 Jan;42(Database issue):D756-63. doi: 10.1093/nar/gkt1114. Epub 2013 Nov 19. PMID: 24259432
  3. Current status and new features of the Consensus Coding Sequence database.
    Farrell CM, O'Leary NA, Harte RA, Loveland JE, Wilming LG, Wallin C, Diekhans M, Barrell D, Searle SM, Aken B, Hiatt SM, Frankish A, Suner MM, Rajput B, Steward CA, Brown GR, Bennett R, Murphy M, Wu W, Kay MP, Hart J, Rajan J, Weber J, Snow C, Riddick LD, Hunt T, Webb D, Thomas M, Tamez P, Rangwala SH, McGarvey KM, Pujar S, Shkeda A, Mudge JM, Gonzalez JM, Gilbert JG, Trevanion SJ, Baertsch R, Harrow JL, Hubbard T, Ostell JM, Haussler D, Pruitt KD.
    Nucleic Acids Res. 2014 Jan;42(Database issue):D865-72. doi: 10.1093/nar/gkt1059. Epub 2013 Nov 11. PMID: 24217909
  4. P. falciparum modulates erythroblast cell gene expression in signaling and erythrocyte production pathways.
    Tamez PA, Liu H, Wickrema A, Haldar K.
    PLoS One. 2011 May 4;6(5):e19307. doi: 10.1371/journal.pone.0019307. PMID: 2157324
  5. The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum.
    Osborne AR, Speicher KD, Tamez PA, Bhattacharjee S, Speicher DW, Haldar K.
    Mol Biochem Parasitol. 2010 May;171(1):25-31. doi: 10.1016/j.molbiopara.2010.01.003.Epub 2010 Feb 1. PMID: 20117149
  6. Stage-specific susceptibility of human erythroblasts to Plasmodium falciparum malaria infection.
    Tamez PA, Liu H, Fernandez-Pol S, Haldar K, Wickrema A. Blood. 2009 Oct 22;114(17):3652-5. doi: 10.1182/blood-2009-07-231894. Epub 2009 Aug 25. PMID: 19706885
  7. An erythrocyte vesicle protein exported by the malaria parasite promotes tubovesicular lipid import from the host cell surface.
    Tamez PA, Bhattacharjee S, van Ooij C, Hiller NL, Llinás M, Balu B, Adams JH, Haldar K.
    PLoS Pathog. 2008 Aug 8;4(8):e1000118. doi: 10.1371/journal.ppat.1000118. PMID: 18688278

For Dr. Tamez's full bibliography, please visit PubMed.

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